Inclusion Criteria:

- Patients between the ages 18 and 75 years.

- Patients may be carriers of the Human Immunodeficiency Virus (HIV).

- Patients must have been diagnosed with precancerous lesion(s) of the vulva by tissue
sampling (biopsy-proven vulvar intraepithelial neoplasia grade II or III)

- Patients must be able to come to University Hospital for their initial appointment in
Gynecologic Oncology Clinic, and for the eight follow-up visits in that Clinic
required by the protocol.

Exclusion Criteria:

- Pregnant or patients who are breast feeding a baby.

- Patients who have been diagnosed with a vaginal yeast infection.

- Patients who have undergone prior surgery for precancerous lesion(s) of the vulva.