Comparison of I-124 PET/CT, F-18 FDG PET/CT and I-123 Whole Body Scintigraphy for Recurrent Thyroid Cancer Detection
The management of thyroid cancer patients with suspicion of recurrent disease based on
rising/detectable levels of thyroglobulin (Tg) involves imaging with iodine-123 whole body
scintigraphy (I-123 WBS) and F-18 FDG PET/CT. However, the disease is not always detected.
The use of another iodine isotope (I-124) with positron emitting characteristics for PET/CT
may allow better identification of recurrent disease, thus allowing for more patients to be
treated with I-131 as a curative attempt.
Conducting this study we hope to find whether I-124 PET/CT allows for detection of more
lesions in patients with suspected recurrent thyroid cancer than the current standard of
care represented by I-123 WBS and F-18 FDG PET/CT.
Observational Model: Cohort, Time Perspective: Prospective
United States: Institutional Review Board