Analysis of Disease Progression for Aplastic Anemia, Myelodysplastic Syndrome, Acute Myeloid Leukemia and Benzene Poisoning in Shanghai, China.
The purpose of this study is to identify and characterize blood diseases presenting at
Shanghai hospitals and to compare them with respect to clinical presentation, phenotype,
molecular characteristics, benzene or other exposures and genetic susceptibility. The
format for these studies is a set of clinical series superimposed on a case-control design
that enables integration of detailed clinical and molecular characterizations of disease
pathogenesis together with an evaluation of potential confounding and interacting factors
within a structured statistical analysis of benzene exposure.
Observational Model: Case Control, Observational Model: Natural History, Time Perspective: Longitudinal, Time Perspective: Prospective
Richard D Irons, PhD
University of Colorado at Denver and Health Sciences Ctr.
United States: Institutional Review Board