Trial Information

The Effects of Cross Training on Fatigue and Pain Levels in Breast Cancer Survivors

OBJECTIVES:

- Determine whether a moderate-intensity exercise program comprising cardiorespiratory
and resistance training of the legs, back, abdominal, trunk, and arm musculature vs a
control group attenuates fatigue and pain in breast cancer survivors.

- Determine whether this exercise program will significantly improve the quality of life
of these patients.

- Determine whether this exercise program can significantly reduce the number of days of
absenteeism from work in these patients.

- Determine whether this exercise program can significantly attenuate mood disturbances
in these patients.

OUTLINE: This is a randomized, controlled, pilot study. Patients are randomized to 1 of 2
treatment arms.

- Arm I (exercise program): Patients participate in an exercise program comprising
cardiorespiratory (walking on a treadmill) and resistance training for 1 hour, 3 times
weekly for 12 weeks.

- Arm II (control): Patients undergo no intervention. In both arms, patients complete
questionnaires regarding general health, mood, work attendance, and physical activity
before the start of study treatment and then every 3 weeks for 12 weeks. Patients also
complete a 7-day physical activity diary and sleep diary every 3 weeks.

PROJECTED ACCRUAL: A total of 54 patients will be accrued for this study.