Trial Information
QM-MSP, Ki-67, and Cytomorphology of RPFNA Specimens From High Risk Women
A study to examine the correlation between gene promotor methylation and benign breast
tissue proliferation and cytomorphology collected via random periareolar fine needle
aspiration in postmenopausal women at increased risk for breast cancer.
Inclusion Criteria
Inclusion criteria:
- women at high risk of developing breast cancer determined by family or personal
history
- willing to participate in companion protocol (KUMC HSC#4601) for random periareolar
fine needle aspiration (RPFNA) for correlational studies
Exclusion criteria:
- exclude women who have been on raloxifene, tamoxifen, letrozole, anastrozole or
exemestane within the six months prior to RPFNA
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Prospective
Principal Investigator
Carol J Fabian, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
University of Kansas
Authority:
United States: Institutional Review Board
Study ID:
9933
NCT ID:
NCT00323908
Start Date:
June 2005
Completion Date:
November 2008
Related Keywords:
- Breast Cancer
- Breast Cancer
- prevention
- tissue sampling
- polymorphisms
- steroid and carcinogen metabolism
- Breast Neoplasms