Trial Information

Clinico-pathologic Correlative Study of 3T Magnetic Resonance Spectroscopy in the Localization of Prostate Cancer

The proposed research is enormously relevant to the clinical understanding of early prostate
cancer. We propose to test to see whether characteristic patterns of invivo 3T MRSI
associated metabolites can be identified in correlation with clinically active tumor
reserved on histopathologic analysis of resected specimens. We also plan to demonstrate
that 3T MR spectra of prostate cancer will allow for more detailed metabolic assessment with
higher sensitivity, specificity and accuracy and publish results established from MR spectra
using 1.5T MR units. Functional imaging (eg. molecular imaging such as this) is felt to be
the clinical wave of the future for cancer imaging, and if successful, will assume a very
major role in the detection, assessment, treatment planning and delivery of drugs,
radiation, heat and novel therapeutics in the fight against prostate cancer.