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Quality of Life in Younger Breast Cancer Survivors


N/A
18 Years
78 Years
Open (Enrolling)
Female
Breast Cancer, Cancer Survivor, Cognitive/Functional Effects, Psychosocial Effects of Cancer and Its Treatment, Sexuality and Reproductive Issues, Spiritual Concerns

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Trial Information

Quality of Life in Younger Breast Cancer Survivors


OBJECTIVES:

- Compare the quality of life (physical functioning, psychological functioning, social
functioning, and spiritual functioning) of female breast cancer survivors who were age
45 or younger at the time of diagnosis with the quality of life of female breast cancer
survivors who were age 55 to 70 at time of diagnosis (considering type of surgical
treatment [lumpectomy vs mastectomy], hormonal treatments, and time since diagnosis as
covariates) and age-matched (to the younger group) females with no history of breast
cancer.

- Compare the quality of life (physical functioning, psychological functioning, social
functioning, and spiritual functioning) of partners of breast cancer survivors who were
age 45 or younger at time of diagnosis with the quality of life of partners of breast
cancer survivors who were age 55 to 70 at diagnosis and partners of age-matched (to the
younger group) females with no history of breast cancer.

- Test and compare quality of life models that identify the variables that mediate
between antecedent variables of personal characteristics, diagnostic and treatment
characteristics, and quality of life outcomes in order to determine where interventions
to improve quality of life should be targeted.

- Explore the relationship of partner antecedent, mediating, and outcome variables as
predictors or mediators of outcome variables for breast cancer survivors.

OUTLINE: This is a multicenter study.

Patients, spouse or partner of patients, age-matched acquaintances of patients, and partner
of acquaintances complete questionnaires over 60-90 minutes about personal characteristics,
self-efficacy, coping, social support, health care provider communication, physical,
psychological, social, and spiritual functioning, and quality of life. After completing the
study questionnaires, patients and age-matched acquaintances of patients are interviewed via
telephone over 30 minutes for cognitive function assessment. A random subset of patients and
spouses/partners of patients are interviewed via telephone over 45-60 minutes, using
data-generating and open-ended questions, regarding physical functioning, sexual and
reproductive issues, psychological issues, social impact, and methods used to deal with
breast cancer survivor concerns.

Disease and treatment characteristics of patients are obtained from medical records.

PROJECTED ACCRUAL: A total of 2,697 patients, spouse or partner of patients, age-matched
female acquaintances of patients, and partner of acquaintances will be accrued for this
study.

Inclusion Criteria


DISEASE CHARACTERISTICS:

- Patient

- Female breast cancer survivor with age at initial diagnosis in 1 of the
following ranges:

- 18 to 45

- 55 to 78

- Must have enrolled and participated in ECOG study CLB-9741, E-1199, or E-2197

- Must have received chemotherapy at least 3 years, but no more than 8 years prior
to this study entry

- Disease free at the time of this study entry

- Spouse or partner of the patient, age-matched female acquaintances of the patient (in
the younger patient group), or partner of acquaintances

- Spouse or partner of the patient may be either gender

- Age-matched female acquaintance is defined as within 5 years of age difference
of the patient in younger group (18-45 years of age)

- With a similar level of education and race of the patient

- Not a personal friend of the patient

- No history of breast cancer

PATIENT CHARACTERISTICS:

- Must reside in the continental U.S. and speak English (for patients)

PRIOR CONCURRENT THERAPY:

- See Disease Characteristics

Type of Study:

Observational

Study Design:

N/A

Outcome Measure:

Comparison of the quality of life

Safety Issue:

No

Principal Investigator

Victoria Champion, DNS

Investigator Role:

Study Chair

Investigator Affiliation:

Indiana University Melvin and Bren Simon Cancer Center

Authority:

United States: Federal Government

Study ID:

CDR0000460234

NCT ID:

NCT00309933

Start Date:

October 2005

Completion Date:

Related Keywords:

  • Breast Cancer
  • Cancer Survivor
  • Cognitive/Functional Effects
  • Psychosocial Effects of Cancer and Its Treatment
  • Sexuality and Reproductive Issues
  • Spiritual Concerns
  • cognitive/functional effects
  • spiritual concerns
  • sexuality and reproductive issues
  • psychosocial effects of cancer and its treatment
  • cancer survivor
  • stage I breast cancer
  • stage II breast cancer
  • stage IIIA breast cancer
  • stage IIIB breast cancer
  • stage IIIC breast cancer
  • Breast Neoplasms

Name

Location

Suburban HospitalBethesda, Maryland  20814
Hinsdale Hematology Oncology AssociatesHinsdale, Illinois  60521
Mercy Medical Center - Sioux CitySioux City, Iowa  51104
Siouxland Hematology-Oncology Associates, LLPSioux City, Iowa  51101
St. Luke's Regional Medical CenterSioux City, Iowa  51104
Bronson Methodist HospitalKalamazoo, Michigan  49007
West Michigan Cancer CenterKalamazoo, Michigan  49007-3731
Borgess Medical CenterKalamazooaa, Michigan  49001
Duluth Clinic Cancer Center - DuluthDuluth, Minnesota  55805-1983
CCOP - DuluthDuluth, Minnesota  55805
Miller - Dwan Medical CenterDuluth, Minnesota  55805
Mercy Cancer Center at Mercy Medical CenterCanton, Ohio  44708
MetroHealth Cancer Care Center at MetroHealth Medical CenterCleveland, Ohio  44109
Sanford Cancer Center at Sanford USD Medical CenterSioux Falls, South Dakota  57117-5039
Medical X-Ray Center, PCSioux Falls, South Dakota  57105
Marshfield Clinic - Marshfield CenterMarshfield, Wisconsin  54449
Marshfield Clinic - Indianhead CenterRice Lake, Wisconsin  54868
Memorial Hospital of South BendSouth Bend, Indiana  46601
Rush University Medical CenterChicago, Illinois  60612-3824
CCOP - Northern Indiana CR ConsortiumSouth Bend, Indiana  46601
Saint Joseph Regional Medical CenterSouth Bend, Indiana  46617
CCOP - Scott and White HospitalTemple, Texas  76508
St. Vincent Mercy Medical CenterToledo, Ohio  43608
Cancer Institute of New Jersey at HamiltonHamilton, New Jersey  08690
CCOP - Toledo Community HospitalToledo, Ohio  43623-3456
Waukesha Memorial Hospital Regional Cancer CenterWaukesha, Wisconsin  53188
Medical University of Ohio Cancer CenterToledo, Ohio  43614
Toledo HospitalToledo, Ohio  43606
Mary Babb Randolph Cancer Center at West Virginia University HospitalsMorgantown, West Virginia  26506
St. Vincent Hospital Regional Cancer CenterGreen Bay, Wisconsin  54307-3508
Green Bay Oncology, Limited - EscanabaEscanaba, Michigan  49431
Dickinson County Healthcare SystemIron Mountain, Michigan  49801
St. Mary's Hospital Medical Center - Green BayGreen Bay, Wisconsin  54303
Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer CenterGreen Bay, Wisconsin  54301-3526
Green Bay Oncology, Limited at St. Mary's HospitalGreen Bay, Wisconsin  54303
Bay Area Cancer Care Center at Bay Area Medical CenterMarinette, Wisconsin  54143
Green Bay Oncology, Limited - Oconto FallsOconto Falls, Wisconsin  54154
Green Bay Oncology, Limited - Sturgeon BaySturgeon Bay, Wisconsin  54235
Baptist Cancer Institute - JacksonvilleJacksonville, Florida  32207
Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical SchoolNew Brunswick, New Jersey  08903
Gundersen Lutheran Center for Cancer and BloodLa Crosse, Wisconsin  54601
Robert H. Lurie Comprehensive Cancer Center at Northwestern UniversityChicago, Illinois  60611
Decatur Memorial Hospital Cancer Care InstituteDecatur, Illinois  62526
Elkhart General HospitalElkhart, Indiana  46515
Howard Community HospitalKokomo, Indiana  46904
South Bend ClinicSouth Bend, Indiana  46617
Lakeland Regional Cancer Care Center - St. JosephSt. Joseph, Michigan  49085
Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital MarltonMarlton, New Jersey  08053
Fox Chase Virtua Health Cancer Program at Virtua West JerseyVoorhees, New Jersey  08043
Fox Chase Cancer Center - PhiladelphiaPhiladelphia, Pennsylvania  19111-2497
Hematology Oncology Associates - SkokieSkokie, Illinois  60076
Hematology and Oncology AssociatesChicago, Illinois  60611
Ingalls Cancer Care Center at Ingalls Memorial HospitalHarvey, Illinois  60426
Midwest Center for Hematology/OncologyJoliet, Illinois  60432
North Shore Oncology and Hematology Associates, Limited - LibertyvilleLibertyville, Illinois  60048
Center for Cancer Therapy at LaPorte Hospital and Health ServicesLa Porte, Indiana  46350
Hickman Cancer Center at Bixby Medical CenterAdrian, Michigan  49221
Community Cancer Center of MonroeMonroe, Michigan  48162
Wood County Oncology CenterBowling Green, Ohio  43402
Lima Memorial HospitalLima, Ohio  45804
St. Luke's HospitalMaumee, Ohio  43537
Northwest Ohio Oncology CenterMaumee, Ohio  43537
Toledo Clinic - OregonOregon, Ohio  43616
St. Charles Mercy HospitalOregon, Ohio  43616
North Coast Cancer Care, IncorporatedSandusky, Ohio  44870
Mercy Hospital of TiffinTiffin, Ohio  44883
Toledo Clinic, Incorporated - Main ClinicToledo, Ohio  43623
Fulton County Health CenterWauseon, Ohio  43567
Bryn Mawr HospitalBryn Mawr, Pennsylvania  19010
Lankenau Cancer Center at Lankenau HospitalWynnewood, Pennsylvania  19096
Lancaster General HospitalLancaster, Pennsylvania  17604-3555
Hematology Oncology Associates of Illinois - BerwynBerwyn, Illinois  60402
Evanston HospitalEvanston, Illinois  60201-1781
La Grange Oncology Associates - GenevaNaperville, Illinois  60563
Cancer Care and Hematology Specialists of Chicagoland - NilesNiles, Illinois  60714
McFarland Clinic, PCAmes, Iowa  50010
Haematology-Oncology Associates of Ohio and Michigan, PCLambertville, Michigan  48144
Mercy Memorial Hospital - MonroeMonroe, Michigan  48162
North Coast Cancer Care - ClydeClyde, Ohio  43410
Hematology Oncology CenterElyria, Ohio  44035
Flower Hospital Cancer CenterSylvania, Ohio  43560
St. Anne Mercy HospitalToledo, Ohio  43623
Guthrie Cancer Center at Guthrie Clinic SayreSayre, Pennsylvania  18840
Fredericksburg Oncology, IncorporatedFredericksburg, Virginia  22401
Marshfield Clinic - Chippewa CenterChippewa Falls, Wisconsin  54729
Marshfield Clinic Cancer Care at Regional Cancer CenterEau Claire, Wisconsin  54701
Marshfield Clinic - Lakeland CenterMinocqua, Wisconsin  54548
Ministry Medical Group at Saint Mary's HospitalRhinelander, Wisconsin  54501
Marshfield Clinic at Saint Michael's HospitalStevens Point, Wisconsin  54481
Marshfield Clinic - Wausau CenterWausau, Wisconsin  54401
Marshfield Clinic - Weston CenterWeston, Wisconsin  54476
Marshfield Clinic - Wisconsin Rapids CenterWisconsin Rapids, Wisconsin  54494
Regional Cancer Center at Memorial Medical CenterSpringfield, Illinois  62781-0001
Regional Cancer Center at Oconomowoc Memorial HospitalOconomowoc, Wisconsin  53066
Manchester Memorial HospitalManchester, Connecticut  06040-4188
MBCCOP - Meharry Medical College - NashvilleNashville, Tennessee  37208-3599
Cancer Center at Phoenixville HospitalPhoenixville, Pennsylvania  19460
York Hospital's Oncology Treatment CenterYork, Maine  03909
Cancer Center of Paoli Memorial HospitalPaoli, Pennsylvania  19301-1792
CCOP - Main Line HealthWynnewood, Pennsylvania  19096
Jersey Shore Cancer Center at Jersey Shore University Medical CenterNeptune, New Jersey  07754-0397
Mercy Regional Cancer CenterJanesville, Wisconsin  53547
Community Hospital of the Monterey Peninsula Comprehensive Cancer CenterMonterey, California  93940
Clarian Arnett Cancer CareLafayette, Indiana  47904