Trial Information

Intraperitoneal Microdialysis Monitoring of Patients During the Early Postoperative Period After LAR With Reference to Early Diagnosis of Anastomotic Leakage

Patients undergoing LAR for recto-sigmoid cancer is subjected to peritoneal microdialyses
during the postoperative period until discharge. Subcutaneous microdialysis serve as
control. Samples are collected every 4-hour. Samples will be analyzed continuously but the
results will not be included in the clinical evaluation of the patient.

Patients undergoing abdomino-perineal rectal resection will serve as a control group.

A total of 50 patients will be included in this pilot study. The results of the peritoneal
microdialyses will be compared with the clinical course in each patient. The results form
the uncomplicated courses will be used to define the normal variations in peritoneal
microdialysis. This will be compared to results from patients with various complications.

The study is approved by the local scientific ethical committee No. ------