Inclusion Criteria:

- Males and females 18 years of age and older with a confirmed diagnosis of
non-small-cell lung cancer (NSCLC) who have failed at least one prior treatment for
NSCLC.

- Patients must have proven disease by CT scan or MRI.

- Patients must be at least 4 weeks from any chemotherapy for cancer or from any
surgeries or from any treatment using an investigational drug.

- Patients must be 2 weeks out from radiation therapy.

- At screening the patient must have normal lab results and can not be pregnant.

- Women and men must agree to practice adequate birth control during the study.

- Patient has the ability to understand and sign the consent form.

Exclusion Criteria:

- Patient had prior treatment with vorinostat or erlotinib.

- Patient has any of the following conditions: active infections including hepatitis B
or C, unstable brain metastases, swallowing difficulties, heart problems, significant
eye abnormalities, drug or alcohol abuse, mental illness or pregnancy.