Acupuncture for Hot Flashes in Prostate Cancer Patients
- Determine the impact of acupuncture therapy on the frequency and intensity of hot
flashes and the quality of life of patients with prostate cancer undergoing androgen
- Determine if blood serotonin and urinary 5-HIAA are increased in patients treated with
- Determine if plasma calcitonin gene-related peptide and MHPG are reduced in patients
with hot flashes due to androgen deprivation treated with acupuncture.
- Determine the ability of tongue diagnosis, a traditional Chinese clinical assessment
method, to predict clinical and biological changes in these patients.
- Determine the effect of acupuncture on insomnia and loss of vitality caused by hot
flashes in these patients.
OUTLINE: Patients undergo acupuncture for 30 minutes twice weekly for 4 weeks and then once
weekly for an additional 6 weeks.
Quality of life is assessed at baseline, at weeks 2, 4, 6, and 10, and then at 6 weeks after
completion of study treatment.
After completion of study treatment, patients are followed at 6 weeks.
PROJECTED ACCRUAL: A total of 25 patients will be accrued for this study.
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Reduced hot flash frequency and intensity as measured by hot flash score from hot flash diary at 4 weeks after initiation of study treatment
Weeks 4 after initiation of study treatment.
Tomasz M. Beer, MD
OHSU Knight Cancer Institute
United States: Federal Government
|OHSU Knight Cancer Institute||Portland, Oregon 97239|
|Portland VA Medical Center||Portland, Oregon 97239|