Phase III Randomized Study of Immediate Versus Luteal Phase Adjuvant Oophorectomy and Tamoxifen in Premenopausal Women With Hormone Receptor-positive Breast Cancer
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
evaluate the impact of the timing in the menstrual cycle of simultaneous mastectomy and oophorectomy on disease-free survival from operable breast cancer.
two- to three-year accrual and initial two or more years of follow-up period
Richard R. Love, M.D.
Ohio State University
United States: Institutional Review Board