A Randomized Controlled Trial of Chemotherapy With 5FU and Cisplatin Before and After Surgery for Stage II,III Squamous Cell Carcinoma of the Thoracic Esophagus:JCOG9907
The previous study JCOG9204 showed that postoperative adjuvant chemotherapy with cisplatin
and fluorouracil has a detectable preventive effect on relapse in patients with esophageal
squamous cell carcinoma compared with surgery alone.(J Clin Oncol 2003;21:4592-4596)
Therefore the standard treatment for stage II and III esophageal cancer is adjuvant
chemotherapy after surgery.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Disease free survival
Nobutoshi Ando, M.D.
Tokyo Dental College Ichikawa General Hospital
Japan: Ministry of Health, Labor and Welfare