Trial Information
Dexamethasone as Palliative Treatment in Addition to Radiation Therapy for Patients With Brain Metastases: A Prospective Study
Inclusion Criteria:
- Known diagnosis of cancer (even if primary unknown)
- Brain metastases (single or multiple) confirmed by imaging (CT, MRI)
- No contraindication for RT/steroids
- Patient will be treated with Whole Brain Radiation Therapy
- Informed consent
Exclusion Criteria:
- Primary cancer is lymphoma or leukemia
- Complete surgical excision of brain metastases
- Patient was on steroids for more then 2 weeks prior to entering the study
- Confusion or other factors that would impair ability to assess symptoms
Type of Study:
Interventional
Study Design:
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Outcome Measure:
To perform an adequate statistical evaluation of patients regarding the role of steroid therapy in managing patients with cerebral metastases.
Principal Investigator
Andrea Bezjak, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Princess Margaret Hospital, Canada
Authority:
Canada: Ethics Review Committee
Study ID:
UHN REB 03-0662-C
NCT ID:
NCT00188864
Start Date:
November 2003
Completion Date:
Related Keywords:
- Neoplasm Metastasis
- Neoplasms
- Neoplasm Metastasis
- Neoplasms, Second Primary