Chemotherapy Plus Local Surgical Treatment in Children With Intraocular Germ-Line Retinoblastoma
Phase 2
N/A
N/A
N/A
N/A
Open (Enrolling)
Both
Retinoblastoma, Retinal Neoplasms
Both
Retinoblastoma, Retinal Neoplasms
Trial Information
Chemotherapy Plus Local Surgical Treatment in Children With Intraocular Germ-Line Retinoblastoma
Inclusion Criteria
Eligibility Criteria:
- Initial clinical diagnosis of Retinoblastoma, with Bilateral tumors, OR Unilateral
tumor with hope for salvage of vision AND Multiple primary tumors, or positive family
history for retinoblastoma, or age < 12 months
- No prior antitumor therapy (except enucleation of one eye)
- At least one tumor exceeds 6 mm in diameter
- No evidence of dissemination outside the globe
- Signed IRB-approved informed consent
- Patient/family available for follow-up
Type of Study:
Interventional
Study Design:
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Outcome Measure:
To determine if a multimodal approach can provide durable control of retinoblastoma and specifically:
Principal Investigator
Stewart Goldman, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Ann & Robert H Lurie Children's Hospital of Chicago
Authority:
United States: Institutional Review Board
Study ID:
CNS 0294
NCT ID:
NCT00179920
Start Date:
April 1996
Completion Date:
September 2006
Related Keywords:
- Retinoblastoma
- Retinal Neoplasms
- Neoplasms
- Retinoblastoma
- Retinal Neoplasms
Name | Location |
|---|---|
| Children's Memorial Hospital | Chicago, Illinois 60614 |
