Prolonged Smoking Cessation Using Prescription Step Care
A common approach to increasing long-term adherence and control of chronic medical problems
such as hypertension in both general and preventive medicine is the concept of step care.
Despite a high degree of interest in applying the step care model to smoking cessation
(Abrams et al., 1996; Hughes, 1994), little empirical work has been conducted utilizing this
treatment approach. The purpose of this study is to evaluate the long-term efficacy of a
step care model for smoking cessation that is disseminable in primary care settings. With
that introduction, we propose the following specific aims:
Aim 1: To enroll approximately 400 adult cigarette smokers recruited mainly from primary
Aim 2: To randomize these participants to: 1) State of the Art Smoking Cessation + Recycling
or 2) State of the Art Smoking Cessation + Step Care; and
Aim 3: To evaluate the long-term (24 months post-randomization) relative success of the
interventions. It is predicted that long-term cessation rates will be significantly higher
in the step care condition.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Long term smoking cessation using both prolonged and point prevalence abstinence criteria
Robert C. Klesges, Ph.D.
United States: Institutional Review Board
|Mayo Clinic||Rochester, Minnesota 55905|
|University of Tennessee||Memphis, Tennessee 38163|