Breast MRI Screening in Women Treated With Mediastinal Irradiation for Hodgkin's Disease
- The screening breast MRI and mammography will be performed 6 months or longer after the
last mammogram. For pre-menopausal women, the screening will be performed during the
second week of the menstrual cycle to reduce cycle-related breast changes. As much as
possible, the breast MRI and mammogram are to be performed on the same day.
- On the day of the breast imaging studies, the patient will also be asked to fill out a
baseline breast health questionnaire, which includes questions on time since radiation
therapy, prior screening history, history of prior benign breast biopsies, menopausal
status, prior hormonal therapy use, etc.
- In patients with suspicious findings or findings highly suggestive of malignancy, the
abnormal findings will be reviewed with the patient and recommendations will be made
for a biopsy.
Observational Model: Case-Only, Time Perspective: Prospective
To compare the sensitivity, specificity, positive and negative predictive value of mammography and breast MRI for breast cancer detection in women treated for Hodgkin's disease.
Andrea K. Ng, MD
Dana-Farber Cancer Institute
United States: Institutional Review Board
|Beth Israel Deaconess Medical Center||Boston, Massachusetts 02215|
|Brigham and Women's Hospital||Boston, Massachusetts 02115|
|Dana-Farber Cancer Center||Boston, Massachusetts 02115|