The Quality of Life of Adult Survivors Who Received a Marrow Transplant as a Child
- Determine the extent to which adult cancer survivors who have undergone prior bone
marrow or peripheral blood stem cell transplantation for a pediatric hematologic
malignancy require ongoing health care and whether these needs change with increasing
time after transplantation.
- Correlate physical capabilities, body image, physical limitations, including sexuality
issues which alter or influence lifestyle, with time after transplantation in these
- Determine whether cognitive abilities relative to memory and neurobehavioral ratings
change with increasing time after transplantation in these patients.
- Correlate social and relationship abilities with length of time after transplantation
in these patients.
OUTLINE: Patients and siblings complete a self-report quality of life questionnaire,
including outcome assessments of neuroendocrine function, cognitive abilities, physical
capability, and psychosocial behavior.
PROJECTED ACCRUAL: Approximately 750 patients (375 adult cancer survivors [case group] and
375 siblings [control group]) will be accrued for this study within 7 years.
Neuroendocrine status of disease-free childhood transplant patients at 5 years after transplant and ≥ age 18
Jean E. Sanders, MD
Fred Hutchinson Cancer Research Center
United States: Federal Government
|Fred Hutchinson Cancer Research Center||Seattle, Washington 98109|