Bioavailability and Effectiveness of Transdermally Administered Morphine
Patients will participate in two arms of the trial, one in which morphine will be
administered transdermally, and, after a 3 day wash out period, one in which morphine will
be administered subcutaneously. Blood draws will be done after both dosing methods in order
to compare blood levels of morphine by the different routes.
Allocation: Randomized, Endpoint Classification: Bio-availability Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
detectable morphine levels in serum
Canada: Health Canada