Inclusion Criteria:

- Subjects with non-myeloid malignancies planning to receive cyclic chemotherapy for 8
additional weeks or more

- Anemia (hemoglobin [hgb] greater than or equal to 9.0g/dL and less than or equal to
11.0 g/dL) related to cancer and chemotherapy

- Karnofsky performance status of greater than or equal to 50%

- Serum bilirubin less than or equal to 2.5 times the upper limit of normal range and
serum creatinine concentration of less than or equal to 2.0 mg/dL

Exclusion Criteria:

- Acute myelogenous leukemia (AML), chronic myelogenous leukemia (CML), or
myelodysplastic syndromes

- Hematologic disorder previously associated with anemia

- Active bleeding

- Iron deficiency

- Received erythropoietic therapy within 14 days prior to randomization

- Unstable cardiac disease

- Known positive human immunodeficiency virus antibody or hepatitis B surface antigen

- Known positive antibody response to any erythropoietic agent

- Currently enrolled in, or has not yet completed at least 30 days since ending other
investigational device or drug trial or is receiving investigational agent(s) not
approved for any indication

- Pregnant or breast feeding

- Red blood cell (RBC) transfusion within 4 weeks of screening

- Known hypersensitivity to any recombinant mammalian-derived product