Trial Information

Radio-Surgical Treatment of Breast Cancer of Women Aged Over 70: Phase II Trial of Feasibility and Reproducibility of a Concentrated and Focalized Radiotherapy

OBJECTIVES:

Primary

- Determine reproducibility of localized and concentrated adjuvant radiotherapy, in terms
of isodose curve and dose heterogeneity, in older women with stage I or II breast
cancer.

Secondary

- Determine the impact of this regimen on Katz's Activity of Daily Living score and
Lawton's Instrumental Activity of Daily Living score in these patients.

- Determine relapse-free survival of patients treated with this regimen.

- Determine overall and specific survival of patients treated with this regimen.

- Determine the cosmetic result, as assessed by the patient, surgeon, and radiologist, of
this regimen in these patients.

- Determine the direct and indirect costs of this regimen in these patients.

OUTLINE: This is a multicenter, open-label, nonrandomized study.

Patients undergo surgery. After surgery, patients undergo radiotherapy twice daily for 5
days.

PROJECTED ACCRUAL: A total of 42 patients will be accrued for this study.