Inclusion Criteria:

- Healthy male between the ages of 16 years and 23 years and 364 days. For the MSM
substudy, between the ages of 16 years and 26 years and 364 days.

- No clinical evidence of genital lesions suggesting sexually-transmitted disease, and
no history of anogenital warts

- Additional criteria will be discussed with you by the physician

Exclusion Criteria:

- Concurrently enrolled in a clinical study involving collection of genital specimens

- History of known prior vaccination with an HPV vaccine

- Received an inactivated vaccine within 14 days or a live virus vaccine within 21 days
prior to enrollment

- History of a severe allergic reaction that required medical intervention

- Received any immune globulin or blood-derived products within 6 months prior to the
first study injection

- History of splenectomy, immune disorders, or receiving immunosuppressives

- Immunocompromised or diagnosed with HIV infection

- Known thrombocytopenia or any coagulation disorder that would contraindicate
intramuscular injections

- History of recent or ongoing alcohol or drug abuse