Contingency Management to Enhance Smoking Cessation for Cancer Survivors: A Proof of Concept Trial
- Compare the feasibility of a multi-component smoking cessation intervention comprising
bupropion and counseling with or without contingency management (cash reward) for
cancer survivors who continue to smoke.
- Compare 7-day point-prevalence abstinence rates in patients treated with these smoking
- Determine the characteristics of these patients that predict success at quitting
OUTLINE: This is a randomized, multicenter study. Patients are randomized to 1 of 2 smoking
cessation intervention arms.
- Arm I: Patients receive oral bupropion twice daily on weeks 1-12 and brief practical
counseling (i.e., problem-solving strategies, stimulus control, stress management, and
social support) on weeks 1-6.
- Arm II: Patients receive treatment as in arm I and contingency management (i.e.,
monetary reinforcement for not smoking) on weeks 1-6.
In both arms, treatment continues in the absence of unacceptable toxicity.
Patients are followed at 12 and 24 weeks after the completion of the smoking cessation
PROJECTED ACCRUAL: A total of 100 patients (50 per intervention arm) will be accrued for
this study within 8 months.
Allocation: Randomized, Primary Purpose: Prevention
Glen D. Morgan, PhD
NCI - Division of Cancer Control and Population Science
United States: Federal Government
|Tobacco Control Research Branch||Rockville, Maryland 20852|