Mucositis is a common side effect to chemotherapy and radiotherapy involving the formation
of erythema and ulcerative lesions in the mouth. Mucositis can be serious, resulting in pain
requiring interventions such as analgesic medications and the use of parenteral feedings.
Currently, no standard therapy is available to prevent or treat mucositis.
Masking: Open Label, Primary Purpose: Treatment
To characterize the PK profile of 3 daily intravenous (IV) doses of rHuKGF before total body irradiation (TBI) / high-dose chemotherapy conditioning treatment and after PBPC transplantation
United States: Food and Drug Administration