Trial Information

Ethics Study To Understand The Decision Making Process Of Phase I Cancer Patients

OBJECTIVES:

- Determine the range of personality traits of patients enrolled in a phase I clinical
trial.

- Determine these patients' understanding of their medical situation and prognosis.

- Determine these patients' understanding of risks and benefits of phase I clinical
trials.

- Determine these patients' reasons for participating in a phase I clinical trial.

- Determine the risk/benefit trade-offs of these patients.

- Determine the existential outlook of these patients.

- Determine the information gathering nature of these patients.

OUTLINE: This is a multicenter study.

Before beginning phase I clinical trial treatment, patients complete a survey over 30-45
minutes administered by an interviewer. Patients then self-administer the Temperament and
Character Inventory assessment over 30 minutes.

PROJECTED ACCRUAL: Approximately 250 patients will be accrued for this study within 6
months.