Pilot Study: Radiofrequency Ablation Of Resectable Non-Small Cell Lung Cancer
18 Years
N/A
Both
Lung Cancer
Trial Information
Pilot Study: Radiofrequency Ablation Of Resectable Non-Small Cell Lung Cancer
OBJECTIVES:
- Determine the acute effects of intraoperative radiofrequency tumor ablation (RFA) in
patients with resectable non-small cell lung cancer.
- Determine the treatment-related toxicity in patients treated with this therapy.
- Determine the dimensions of the RFA lesion produced by the ablation procedure in these
patients.
OUTLINE: Patients undergo intraoperative radiofrequency tumor ablation over 10-15 minutes
for each tumor immediately followed by tumor resection.
PROJECTED ACCRUAL: A maximum of 20 patients will be accrued for this study.
Inclusion Criteria
DISEASE CHARACTERISTICS:
- Diagnosis of malignant non-small cell lung cancer (NSCLC)
- Intraoperative needle biopsy confirmation allowed
- Resectable disease (stage I or II)
- All tissue to be treated by radiofrequency tumor ablation must be completely
contained within boundaries of planned lung resection
- Medically fit to undergo lung resection
PATIENT CHARACTERISTICS:
Age:
- Over 18
Performance status:
- Not specified
Life expectancy:
- Not specified
Hematopoietic:
- Not specified
Hepatic:
- Not specified
Renal:
- Not specified
Other:
- Not pregnant or nursing
PRIOR CONCURRENT THERAPY:
Biologic therapy:
- No prior or concurrent biologic therapy
Chemotherapy:
- No prior or concurrent chemotherapy
Endocrine therapy:
- No prior or concurrent endocrine therapy
Radiotherapy:
- No prior or concurrent radiotherapy
Surgery:
- See Disease Characteristics
Other:
- No other prior therapy for NSCLC
Type of Study:
Interventional
Study Design:
Primary Purpose: Treatment
Principal Investigator
Walter J. Scott, MD, FACS
Investigator Role:
Study Chair
Investigator Affiliation:
Fox Chase Cancer Center
Authority:
United States: Federal Government
Study ID:
CDR0000069389
NCT ID:
NCT00039507
Start Date:
June 2002
Completion Date:
February 2004
Related Keywords:
- Lung Cancer
- stage I non-small cell lung cancer
- stage II non-small cell lung cancer
- Carcinoma, Non-Small-Cell Lung
- Lung Neoplasms
Name | Location |
|---|---|
| Fox Chase Cancer Center | Philadelphia, Pennsylvania 19111 |
