Phase II Pilot Study Of Moderate Dose Radiotherapy For Inoperable Aggressive Fibromatoses
- Determine the efficacy of moderate-dose radiotherapy, in terms of local control, in
patients with aggressive fibromatoses.
- Determine the acute and late side-effects of this regimen in these patients.
OUTLINE: This is a multicenter study.
Patients receive radiotherapy 5 days a week for 5.5 weeks for a total of 56 Gy in 28
Patients are followed every 3 months for 2 years and then every 6 months thereafter.
PROJECTED ACCRUAL: A total of 40 patients will be accrued for this study within 3 years.
Primary Purpose: Treatment
Local control as assessed by MRI at 3 years
R. B. Keus, MD
Arnhems Radiotherapeutisch Instituut
United States: Federal Government