Computerized Tomographic Colonography: Performance Evaluation in a Multicenter Setting
OBJECTIVES: I. Compare retrospectively the accuracy of computerized tomographic colonography
(CTC) vs pathology and colonoscopy in the detection of clinically important colorectal
neoplasia, defined as at least one proven lesion with a diameter measuring at least 1 cm.
II. Compare the physician image display preferences and interpretation time across three
viewing platforms for CTC images.
OUTLINE: This is a retrospective, multicenter study. Radiologists evaluate each patient's
optimal diagnostic computerized tomographic colonography (CTC) data. Patients' CTC findings
are evaluated by a radiologist at a central facility using an imaging display software
platform from General Electric, Vital Images, or the Mayo Clinic. CTC findings are compared
with conventional colonoscopy findings and pathologic analysis. A comparison is made between
physician image display preferences and interpretation time across three viewing platforms
for CTC images.
PROJECTED ACCRUAL: A total of 90 patients will be accrued for this study.
Primary Purpose: Diagnostic
C. Daniel Johnson, MD
United States: Federal Government
|Mayo Clinic Cancer Center||Rochester, Minnesota 55905|
|University of Alabama Comprehensive Cancer Center||Birmingham, Alabama 35294|
|Jonsson Comprehensive Cancer Center, UCLA||Los Angeles, California 90095-1781|
|Duke Comprehensive Cancer Center||Durham, North Carolina 27710|
|Comprehensive Cancer Center of Wake Forest University Baptist Medical Center||Winston-Salem, North Carolina 27157-1082|
|Milton S. Hershey Medical Center||Hershey, Pennsylvania 17033|
|NYU School of Medicine's Kaplan Comprehensive Cancer Center||New York, New York 10016|
|Mallinckrodt Institute of Radiology||Saint Louis, Missouri 63110|
|Boston Medical Center||Boston, Massachusetts 02118|
|Veterans Affairs Medical Center - San Francisco||San Francisco, California 94121|
|Emory University School of Medicine||Atlanta, Georgia 30322|