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N/A
5 Years
N/A
Open (Enrolling)
Both
Schwannoma, Vestibular, Neurofibromatosis 2, Meningioma

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Trial Information


PROTOCOL OUTLINE: Data on the clinical course and growth rate of NF2-related tumors in
patients with neurofibromatosis 2. Patients are evaluated each year on a cranial and a
spinal MRI, eye tests, hearing tests, quality of life, neurological tests, and physical
functioning.

Inclusion Criteria


PROTOCOL ENTRY CRITERIA:

--Disease Characteristics--

- Diagnosed with neurofibromatosis 2 on or after 01/01/93

- Must meet one of the following conditions:

Bilateral vestibular schwannoma OR Family history of neurofibromatosis 2 (first degree
family relative) AND Unilateral vestibular schwannoma at under 30 years OR Any 2 of the
following: Meningioma Glioma Schwannoma Juvenile posterior subcapsular lenticular
opacity/juvenile cortical cataract

- No plans to treat vestibular schwannoma in next 12 months

--Prior/Concurrent Therapy--

- Not specified

--Patient Characteristics--

- Age: 5 and over

Type of Study:

Observational

Study Design:

Observational Model: Natural History, Time Perspective: Longitudinal

Principal Investigator

William H. Slattery, III

Investigator Role:

Study Chair

Investigator Affiliation:

House Ear Institute

Authority:

Unspecified

Study ID:

199/14226

NCT ID:

NCT00004483

Start Date:

January 2002

Completion Date:

Related Keywords:

  • Schwannoma, Vestibular
  • Neurofibromatosis 2
  • Meningioma
  • Meningioma
  • Neurilemmoma
  • Neurofibromatoses
  • Neurofibromatosis 1
  • Osteitis Fibrosa Cystica
  • Neurofibromatosis 2
  • Neuroma, Acoustic

Name

Location

House Ear InstituteLos Angeles, California  90057-9927