CRYOSURGICAL DESTRUCTION OF SURGICALLY INCURABLE LIVER TUMORS
OBJECTIVES: I. Assess the safety and efficacy of liquid nitrogen necrosis of liver lesions
using a commercially available intraoperative cryosurgical system, with placement of the
cryoprobe and subsequent monitoring by high-resolution ultrasound. II. Use this technique on
selected patients with surgically unresectable metastatic or primary liver cancer whose
disease appears confined to the liver and who are potentially curable if all tumor in the
liver can be destroyed. III. Quantitate the quality and duration of survival, identify
recurrence of hepatic malignant disease, and identify any morbidity from the procedure.
OUTLINE: Cryosurgery. Liquid nitrogen freezing of tumor using a cryoprobe placed and
maintained under ultrasound guidance.
PROJECTED ACCRUAL: 50 patients will be treated.
Primary Purpose: Treatment
Greg V. Stiegmann, MD
University of Colorado, Denver
United States: Federal Government
|University of Colorado Cancer Center||Denver, Colorado 80262|