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A Pilot Study of Adherence to Oral Medication and Health Beliefs of Adolescents With HIV and Their Mothers

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Acquired Immunodeficiency Syndrome, HIV Infections

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Trial Information

A Pilot Study of Adherence to Oral Medication and Health Beliefs of Adolescents With HIV and Their Mothers

The proposed study has two specific aims 1) to gather data about treatment adherence levels
among adolescents (11-21 years) with HIV and 2) to obtain information about the adolescents
and mothers' health beliefs and examine their relationship to the adolescents' adherence
levels. This pilot study is designed to gather preliminary data about the feasibility of
using several new measures with this population. To achieve these aims, a convenience
sample of approximately 45 adolescents with HIV will be recruited. The adolescents and
their mothers will complete a brief questionnaire about their health beliefs. A 24-hour
recall interview format will be used to assess the adolescents' treatment adherence to
prescribed oral medication. The adolescent will complete recall interviews on three random
days over a two week period. Data analysis will be primarily descriptive, but will be used
to generate more specific hypotheses for future research studies. The long-term goal of
this research is to better identify adolescents with HIV at risk for non-adherence and
design empirically derived interventions to improve their adherence levels. The health
beliefs measure may also be useful in identifying irrational beliefs about the illness or
treatment that can then be targeted for cognitive restructing in psychological

Inclusion Criteria

Subjects must be between the ages of 11 and 21 years.

Subjects must be diagnosed with HIV for at least one year (to ensure sufficient
opportunity to experience living with a chronic condition such that adherence level is
unlikely to be the result of skill or knowledge deficits).

Subjects must be prescribed oral medications (e.g., pills, liquids, inhaler) to be taken
on a daily basis.

Subjects must be living with same female caregiver for at least one year.

Subjects must have a telephone number where he/she can be contacted during the two weeks
after recruitment.

The adolescent and mother must be able to provide informed consent.

Adolescents must not have mental retardation or developmental delay that would prevent the
adolescent from reading and comprehending the questionnaire.

Type of Study:


Study Design:



United States: Federal Government

Study ID:




Start Date:

June 1998

Completion Date:

March 2000

Related Keywords:

  • Acquired Immunodeficiency Syndrome
  • HIV Infections
  • AIDS
  • Compliance
  • HIV
  • Medication
  • Perceived Threat
  • Teenagers
  • Acquired Immunodeficiency Syndrome
  • HIV Infections
  • Immunologic Deficiency Syndromes



National Cancer Institute (NCI) Bethesda, Maryland  20892