Inclusion Criteria:

- Diagnosis of breast cancer (stages I (≥1 cm), stage II, or stage IIIA, B, C excluding
distant metastasis) diagnosed between 6 months and 5 years earlier; after initial
therapies are completed, diagnosed between six months and five years earlier

- BMI between 25 to 45 kg/m2

- Able to comply with all required study procedures and schedule

Exclusion Criteria:

- Serious medical condition or psychiatric illness

- Inability to be moderately physically active

- Obesity of known endocrine origin (e.g., untreated hypothyroidism, PCOS)

- Currently enrolled in a weight loss program

- Current use of weight loss medication or supplements

- Previous surgical procedures for weight reduction

- Planning weight loss surgery in the next 2 years.

- 6+ months use of meds likely to cause weight gain or prevent weight loss

- Planned surgical procedure that can impact the conduct of the study

- Currently pregnant/breastfeeding

- Planning to become pregnant within the next 2 years

- Have plans to relocate from area within 2 years

- Family relative or close friend is a trial staff member or a study participant

- Any condition which in the opinion of the investigator makes the subject unsuitable
for inclusion in this study