Breast MRI Screening in Women Treated With Mediastinal Irradiation for Hodgkin's Disease
- The screening breast MRI and mammography will be performed 6 months or longer after the
last mammogram. For pre-menopausal women, the screening will be performed during the
second week of the menstrual cycle to reduce cycle-related breast changes. As much as
possible, the breast MRI and mammogram are to be performed on the same day.
- On the day of the breast imaging studies, the patient will also be asked to fill out a
baseline breast health questionnaire, which includes questions on time since radiation
therapy, prior screening history, history of prior benign breast biopsies, menopausal
status, prior hormonal therapy use, etc.
- In patients with suspicious findings or findings highly suggestive of malignancy, the
abnormal findings will be reviewed with the patient and recommendations will be made
for a biopsy.
Observational
Observational Model: Case-Only, Time Perspective: Prospective
To compare the sensitivity, specificity, positive and negative predictive value of mammography and breast MRI for breast cancer detection in women treated for Hodgkin's disease.
5 years
No
Andrea K. Ng, MD
Principal Investigator
Dana-Farber Cancer Institute
United States: Institutional Review Board
05-241
NCT00165412
July 2005
May 2010
Name | Location |
---|---|
Beth Israel Deaconess Medical Center | Boston, Massachusetts 02215 |
Brigham and Women's Hospital | Boston, Massachusetts 02115 |
Dana-Farber Cancer Center | Boston, Massachusetts 02115 |