A Randomized Trial Evaluating Autologous Endometrial Co-Culture Versus Conventional Medium in the Treatment of Infertility
Inclusion Criteria:
- Undergoing In Vitro Fertilization (IVF) or IVF/Intra Cytoplasmic Sperm Injection
(ICSI) at OVO clinic
- Having a prescription of a long, short or an antagonist IVF protocols using both
urinary and synthetic gonadotropins
- Having a single embryo transfer
- Regular menstrual cycles
- Basal follicle stimulating hormone levels less than 10 IU/l within 6 months prior to
entering the study
- anti-mullerian hormone more than 1 ng/ml measured within a year
- Normal sonohysterogram or hysteroscopy done within the last 2 years
- Previously undergone a maximum of 3 IVF cycles
- Documented negative serology tests within 1 year prior recruitment for: Hepatitis B,
Syphilis, HIV based on Health Canada recommendations for treatment in an IVF
laboratory.
Exclusion Criteria:
- Amenorrhea
- Anovulatory cycles
- Polycystic Ovarian syndrome
- Chronic endometritis
- Severe endometriosis
- Hydrosalpinx
- Uterine synechia or Asherman's syndrome
- Submucosal uterine fibroids or intra-cavitary polyps greater than 1cm
- Uterine anomalies
- Use of anticoagulants
- Secretory Azoospermia