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NCI Young Adult Smoking Cessation Evaluation

Phase 2
18 Years
29 Years
Open (Enrolling)
Smoking, Smoking Cessation, Cigarette Smoking, Tobacco, Smoking

Thank you

Trial Information

NCI Young Adult Smoking Cessation Evaluation

This study seeks to assess the effectiveness of the QuitTXT program, a text message
cessation intervention designed for young adult smokers ages 18-29. The QuitTXT program is
a component of a larger web-based tobacco cessation intervention resource provided by the
National Cancer Institute. The program focuses on providing actionable strategies and fact
based information, serving as an engagement tool delivering two-way communication, and
delivering intra- and extra-treatment support. The structure of the QuitTXT program is
designed as a 14-day countdown to quit date with subsequent six weeks of messages.
Throughout the program, users will receive texts that cover a variety of content areas
including tips, informational content, motivational messaging, and keyword responses.

The study seeks to recruit a large sample of young adult smokers ages 18-29 to examine how
exposure to the QuitTXT program affects participants.

There will be 3-arms to the study:

Participants in Arm 1, the control group of the study, will only receive the weekly
assessments asking them of their smoking status.

Participants in Arm 2 will receive a texting program that consists of up to two weeks of
countdown to quit messaging plus assessments messages that all groups receive for a total of
8 weeks.

Participants in Arm 3 will receive the full text messaging program.

All groups will be able to select a quit date within a 7-day window (between 2 and 3 weeks
after they complete the baseline survey). Participants in Arm 3 will receive
motivational/informational messages while participants in group 1 will receive only
assessment messages. Participants in Arm 2 will receive the countdown messages to their quit
date, but not the motivational messaging after their quit date. Like Arm 1, they will only
receive assessment messages after their quit date.

This study will add unique value to the existing literature by teasing out the effect of
some messages vs. frequent, motivational/informational messaging on quit rates and intent to
quit among young adults.

Inclusion Criteria

- For this study, we will recruit smokers aged 18 to 29 who have smoked on at least 5
of the last 30 days and who are interested in stopping smoking in the next 30 days.
To be eligible, a young adult must meet the following criteria:

Ages 18-29 years

Reside in the US

Smoke cigarettes at least 5 days/month

Be interested in quitting cigarette use

Not be involved in a cessation program

Have an active email account

Be able to receive text messages on their cell phone

Be the only member of your household participating in this study

Be willing to share contact information with the study team in order to share information
about the study on a timely basis.

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind, Primary Purpose: Treatment

Outcome Measure:

Key outcome variables included cessation initiation, cessation maintenance, relapse, reduction in cigarette smoking, and period of abstinence from smoking.

Outcome Time Frame:

Assessed at multiple points during the trial

Safety Issue:


Principal Investigator

Erik M Augustson, Ph.D.

Investigator Role:

Principal Investigator

Investigator Affiliation:

National Cancer Institute (NCI)


United States: Federal Government

Study ID:




Start Date:

June 2013

Completion Date:

February 2016

Related Keywords:

  • Smoking
  • Smoking Cessation
  • Cigarette Smoking
  • Tobacco, Smoking
  • Smoking Cessation Clinical Trial
  • Text Messaging Program
  • Smoking Cessation Aid
  • Smoking



National Cancer Institute (NCI), 9000 Rockville PikeBethesda, Maryland  20892