Clinical Utility of Contrast-enhanced Intraoperative Ultrasound in Surgery of Colorectal Liver Metastases. Phase II Clinical Trial.
Hypothesis: Use of contrast ultrasound showed interesting results, which can increase
ultrasonography sensitivity performed during surgery in the evaluation of operable liver
This study is a two-stage phase II multicenter study (Simon's two-stage).
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
The clinical utility will be evaluated in terms of the proposed amendment justified after ultrasound surgery of Intraoperative contrast, compared to the planned following surgery a conventional intraoperative ultrasonography
For each patient, we will consider that CEUS intraoperative clinical utility: if the planned surgery after contrast echocardiography is different from the intraoperative considered after surgery for conventional ultrasound, if the planned surgery after contrast echocardiography Intraoperative warranted.
at time of surgery
EVRARD Serge, PU-PH
France : Agence Française de Sécurité Sanitaire des Produits de Santé