Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer (POUDER)
Patients will be randomly classified into two groups - verum and placebo. The patients in
the experimental arm will receive capsules with broccoli sprout grain containing a total of
90mg sulforaphane active substance per day over one year as nutrition supplement whereas
patients assigned to the placebo group will receive inactive substance (methylcellulose)
with identical capsule and portion distribution.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Main objective is to establish evidence that broccoli sprouts rich in sulforaphane and quercetin as nutritional supplements increase the overall survival of patients with pancreatic ductal adenocarcinoma treated with conventional cytoreductive (radio-) chemotherapy.
Peter Schemmer, Prof.Dr.med.
University of Heidelberg
Germany: Ethics Commission