Trial Information
Plasma Cobalamin, Folate, Pyridoxine and Homocysteine Levels and Thrombosis in Patients With Philadelphia-chromosome-negative Myeloproliferative Neoplasms
Thirty-one new or formerly diagnosed MPN patients who consecutively visitted our outpatient
clinic, as well as 40 age and sex matched healthy controls were enrolled in this study.
Inclusion Criteria:
Adult MPN patients and healthy controls who gave a written consent were included in the
study.
Exclusion Criteria:
Exclusion criteria included not giving a written consent and using medications without an
indication which may have an effect on plasma homocysteine and vitamin levels.
Type of Study:
Observational [Patient Registry]
Study Design:
Observational Model: Cohort, Time Perspective: Prospective
Outcome Measure:
Thrombosis
Outcome Time Frame:
at least 1 year
Safety Issue:
No
Principal Investigator
Ahmet Emre Eskazan, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Istanbul University
Authority:
Turkey: Ethics Committee
Study ID:
HcyMPN
NCT ID:
NCT01878916
Start Date:
January 2003
Completion Date:
June 2004
Related Keywords:
- Thrombosis
- the incidence of thrombosis,
- the effect of Hcy on thrombosis formation,
- the relation between Hcy and plasma vitamin levels,
- to compare these results with the control group
- Myeloproliferative Disorders
- Philadelphia Chromosome
- Thrombosis