Adaptation to Living With a BRCA l/2 Mutation in Carriers and Their Partners
The proposed study aims to describe adaptation and dyadic adjustment in unaffected BRCA1/2
carriers and their partners. It is not fully understood how women and their partners adapt
to highrisk status over time, nor how different aspects of living at risk relate to this
process. Neither psychological adaptation nor dyadic adjustment has been systematically
measured in this population. This study is informed by Lazarus & Folkman's Transactional
Model of Stress and Coping and modifications made to this model for use in studying dyadic
relationships. A crosssectional research design will quantitatively explore the
relationships between the appraisals and timing of risk-related stressors, dyadic coping,
and the outcomes of adaptation and dyadic adjustment. Participants will be recruited from
hereditary breast and ovarian cancer (HBOC) support groups, website postings, listservs, and
clinic patient lists. They will have the option of completing either a paper or online
version of the survey.
Observational
Time Perspective: Retrospective
the primary outcome is psychological adaptation
1 time survey
No
Gillian W Hooker, Ph.D.
Principal Investigator
National Human Genome Research Institute (NHGRI)
United States: Federal Government
999913134
NCT01866865
May 2013
May 2016
Name | Location |
---|---|
Johns Hopkins Bloomberg School of Public Health | Baltimore, Maryland |