Inclusion Criteria:

- Male or female patients between 18-65 years of age with moderately/severely (Crohn's
Disease Activity Index 220-450) active Crohn's disease with/without fistula
formation,

- Patients who are able to provide authorization to use and disclose information
related with the study,

- Proven diagnosis of Crohn's Disease in accordance with international diagnostic
criteria such as European Crohn's and Colitis Organisation (ECCO) guidelines,

- Patients for whom the physician has initiated Crohn's disease treatment with
anti-Tumor Necrosis Factors in accordance with Turkish Ministry of Health regulations
and reimbursements.

Exclusion Criteria:

- Subject has a history of any kind of biological therapy and/or anti-Tumor Necrosis
Factor treatments for Crohn's disease or other indications

- Subject has septic complications (active infection and/or active Tuberculosis,
undrained abscess),

- Patients who have bowel obstructions and fibrotic strictures,

- Subject has received any investigational drug within 30 days prior to the Visit 1 at
baseline,

- For any reason, subject is considered by the investigator to be an unsuitable.