Trial Information
Lung HeXeRT: Advanced Proton, Hyperpolarised 3-helium and 129-xenon Magnetic Resonance Imaging for Lung Cancer Radiotherapy Planning and Evaluation
Inclusion Criteria:
- Patients with an MDT diagnosis of NSCLC based on findings of positive histology,
positive PET scan or growth on serial CT scan requiring CT planning for radiotherapy
treatment
- patients aged over 18
- patients able to undergo MRI scanning.
Exclusion Criteria:
- patients with co-morbid conditions that exclude radiotherapy treatment
- patients who are pregnant or women with child bearing potential
- patients unable to give informed consent
- patients with impaired renal function who can react to gadolinium (Gd-DTPA) 1H MRI
contrast
- patients who do not understand English sufficiently to read the patient information
sheet, provide informed consent or converse with research staff without interpreters.
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Prospective
Outcome Measure:
Percentage of ventilated lung measured using inhaled gas MRI
Outcome Time Frame:
Change between pre treatment (average 10 days before start of treatment) and at 3 months post treatment
Safety Issue:
No
Principal Investigator
Matthew Q Hatton, FRCR, FRCP
Investigator Role:
Principal Investigator
Investigator Affiliation:
University of Sheffield
Authority:
United Kingdom: National Health Service
Study ID:
STH17245
NCT ID:
NCT01859650
Start Date:
July 2013
Completion Date:
Related Keywords: