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Lung HeXeRT: Advanced Proton, Hyperpolarised 3-helium and 129-xenon Magnetic Resonance Imaging for Lung Cancer Radiotherapy Planning and Evaluation


N/A
18 Years
N/A
Not Enrolling
Both
NSCLC

Thank you

Trial Information

Lung HeXeRT: Advanced Proton, Hyperpolarised 3-helium and 129-xenon Magnetic Resonance Imaging for Lung Cancer Radiotherapy Planning and Evaluation


Inclusion Criteria:



- Patients with an MDT diagnosis of NSCLC based on findings of positive histology,
positive PET scan or growth on serial CT scan requiring CT planning for radiotherapy
treatment

- patients aged over 18

- patients able to undergo MRI scanning.

Exclusion Criteria:

- patients with co-morbid conditions that exclude radiotherapy treatment

- patients who are pregnant or women with child bearing potential

- patients unable to give informed consent

- patients with impaired renal function who can react to gadolinium (Gd-DTPA) 1H MRI
contrast

- patients who do not understand English sufficiently to read the patient information
sheet, provide informed consent or converse with research staff without interpreters.

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Percentage of ventilated lung measured using inhaled gas MRI

Outcome Time Frame:

Change between pre treatment (average 10 days before start of treatment) and at 3 months post treatment

Safety Issue:

No

Principal Investigator

Matthew Q Hatton, FRCR, FRCP

Investigator Role:

Principal Investigator

Investigator Affiliation:

University of Sheffield

Authority:

United Kingdom: National Health Service

Study ID:

STH17245

NCT ID:

NCT01859650

Start Date:

July 2013

Completion Date:

Related Keywords:

  • NSCLC

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