Inclusion Criteria:

Age> 18 years

- ASA I-II, WHO 0-1

- mastectomy alone, mastectomy + GGS + mastectomy CA

- No previous history of chronic pain requiring regular intake of analgesics or
long-term

- Failure to take opioids within 30 days before surgery

Exclusion Criteria:

- Long-term treatment analgesic or taking opioids within 30 days before surgery

- Concurrent treatment with a drug test, participation in another therapeutic clinical
trial within <30 days

- proven allergy to local anesthetics of the amide

- Skin Inflammation

- Sepsis local

- Kidney failure, liver failure, severe or poorly controlled diabetes

- Inability to respond to the assessment of pain using a visual analogue scale (VAS) or
a numerical scale (FR).

- mastectomy with immediate breast reconstruction