Kilovoltage Conebeam Imaging Based Adaptive Radiation Therapy for Head & Neck Patients Treated With Intensity Modulated Radiation Therapy
The investigators' secondary objectives for this study are to assess the possibility of
using kV cone beam for treatment replanning as compared to standard the treatment planning,
to determine the need and feasibility of adaptive radiation therapy, to develop concept of
establishing cumulative DVH (C-DVH) with daily updates and compare it to planned DVH
(P-DVH), to identify tolerance margins, to evaluate local control, locoregional control,
distant metastasis, and overall survival, to assess patient quality of life,and to develop
predictors of patients which may benefit from ART.
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Clinical patient response
This will assessed by CT scan or MRI 4-5 weeks post concurrent chemo.
From the date of initiation of radiation therapy, until date of first progression or until date of death (approximately 5 years).
Ken Hu, MD
Beth Israel Medical Center
United States: Institutional Review Board
|Beth Israel Medical Center||New York, New York 10003|