Prospective Pilot Study of Assessment of Breath Hold as a Means to Mitigate the Risk of Radiation-associated Reductions in Regional Cardiac Perfusion in Patients With Left-sided Breast Cancer
The primary objective of this study is to estimate the rate of radiation-associated regional
myocardial perfusion defects in patients 6 months after breast/chestwall radiation with DIBH
for left-sided breast cancer. Cardiac perfusion will be assessed using SPECT cardiac
perfusion scans pre- and 6 months post-radiation.
Observational Model: Cohort, Time Perspective: Prospective
Changes in cardiac perfusion
Cardiac perfusion will be assessed using SPECT cardiac perfusion scans pre- and 6 months post-radiation. Any post-radiation summed-rest score (SRS) > 0 will be counted as a perfusion defect in the calculation of the perfusion defect rate.
6-months post radiation
Timothy M Zagar, MD
University of North Carolina, Chapel Hill
United States: Institutional Review Board
|University of North Carolina at Chapel Hill, Department of Radiation Oncology||Chapel Hill, North Carolina 27599|