Predictive Value of the Distress Thermometer as a Predictive Screening Instrument to Detect Cancer-related Cognitive Impairment in Cancer Patients
Design: Prospective, observational study. All cancer patients of the above mentioned cancer
types receiving an anticancer treatment with curative intent will be asked to participate to
this study. Consenting patients will undergo serial assessment at baseline, and 6 months
after inclusion. Patient will be screened by the Distress Thermometer and 38-item Problem
List followed by a neuropsychological assessment and self-assessment tools.
Observational Model: Cohort, Time Perspective: Prospective
Validation of the Distress Thermometer, accompanied by the 38-item Problem List, as a screening tool to predict cancer-related cognitive decline, measured through standard neuropsychological testing
The primary objective of this observational study is to validate the Distress Thermometer, accompanied by the 38-item Problem List, as a screening tool to predict cancer-related cognitive decline, measured through standard neuropsychological testing in cancer patients receiving curative (adjuvant) radiotherapy, chemotherapy, radiochemotherapy, radiobiotherapy, or targeted therapy.
Philip R Debruyne, MD, PhD
General Hospital Groeninge
Belgium: Ethics Committee