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Evolution of Bone Mineral Density (BMD) in Patients With Lymphoma Undergoing Chemotherapy: Prospective Longitudinal Study Over 12 Months.


Phase 4
18 Years
80 Years
Open (Enrolling)
Both
Lymphoma., Osteoporosis.

Thank you

Trial Information

Evolution of Bone Mineral Density (BMD) in Patients With Lymphoma Undergoing Chemotherapy: Prospective Longitudinal Study Over 12 Months.


Inclusion Criteria:



- Subjects aged 18 to 80 with lymphoma,

- Histological diagnosis of Hodgkin's lymphoma (HL) or non-Hodgkin lymphoma (NHL) of
follicular or aggressive (large cell or other),

- Patients who have not yet started their chemotherapy or who have started for less
than a month

- Patient has signed informed consent.

Exclusion Criteria:

- Pathological fractures at the time of initial diagnosis of lymphoma,

- Compression of neurological epidural,

- Patients receiving treatment for osteoporosis (including bisphosphonates, selective
modulators of estrogen receptor, calcitonin and parathyroid hormone Teriparatide).

- Discovery of osteoporosis or osteopenia fracture during the initial evaluation
requiring the establishment of an osteoporosis treatment,

- Radiotherapy to the lumbar spine or hip studied,

- Location of bone lymphoma in the lumbar spine or hip studied,

- History of disorders affecting bone metabolism (prostate cancer with androgen,
stomach cancer, hyperparathyroidism, hyperthyroidism, uncontrolled ...)

- A person incapable of giving consent personally,

- Pregnant or breastfeeding women,

- Protected Person (under guardianship)

- Patient not affiliated with a social security system.

Type of Study:

Interventional

Study Design:

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Outcome Measure:

Measurement of bone mineral density (BMD).

Outcome Description:

Patients will have a review of bone densitometry.

Outcome Time Frame:

Change from Baseline of bone mineral density at 12 months.

Safety Issue:

No

Principal Investigator

Gandhi DAMAJ, Doctor

Investigator Role:

Principal Investigator

Investigator Affiliation:

CHU d'Amiens France

Authority:

FRANCE: National Security Agency of Medicines and Health Products

Study ID:

PI11-Dr.DAMAJ/PACCOU

NCT ID:

NCT01841814

Start Date:

April 2013

Completion Date:

June 2014

Related Keywords:

  • Lymphoma.
  • Osteoporosis.
  • Lymphoma
  • Osteoporosis
  • Chemotherapy
  • Patient with
  • Lymphoma
  • Osteoporosis

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