Zero Ischemia Laparoscopic Radio Frequency Ablation Assisted Enucleation of Renal Cell Carcinoma With T1a Stage : Clinical Outcomes of a Randomised Controlled Trial
Warm ischemic injury is one of the most important factors affecting renal function in
partial nephrectomy (PN). Zero ischemia partial nephrectomy technique using renal arterial
branch microdissection could protect renal function during surgery, but it requires longer
operative time and more blood loss than conventional partial nephrectomy. The technique of
zero ischemia laparoscopic radio frequency ablation assisted enucleation of renal cell
carcinoma appears to be an alternative that eliminates warm ischemia, preserves the maximal
parenchyma and is oncologically safe. Our study was designed to evaluate this technique in
comparison with the conventional laparoscopic partial nephrectomy.
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
the absolute change in glomerular ﬁltration rate (GFR) of the aﬀected kidney
6 months minus baseline
baseline and 6 months
Yiran Huang, M.D.
China: Ethics Committee