Inclusion Criteria:

- Male or female patients ≥ 18 years of age

- Initially diagnosed or recurrent hepatocellular carcinoma (HCC)

- Unresectable HCC

- Cirrhotic status of Child Pugh class A or B7

- Eastern Cooperative Oncology Group performance status 0 or 1

- single or sum of multiple tumor ≤ 5 cm

- HCC with 3 cm apart from gastrointestinal tract

- The volume of uninvolved must be at least 1000 ml

- Incomplete response after trans-arterial chemo-embolization of 1-5

- A single lesion or multiple lesions including portal vein tumor thrombosis included
in radiation field with one or consecutive sessions of stereotactic body radiation
therapy (SBRT)

- No evidence of an uncontrolled lesion at any other site

- No evidence of complications of liver cirrhosis

- No evidence of uncontrolled inter-current illness

- Patient or guardian must be able to provide verbal and written informed consent

Exclusion Criteria:

- Patient with previous history of abdominal radiation

- Direct invasion to esophagus, stomach or colon by HCC