Inclusion Criteria

Inclusion criteria:

Patients with verified gastric adenocarcinoma but found non-resectable or inoperable
after evaluation in the appropriate multidisciplinary team at St.Olav Hospital. Trondheim
University Hospital. The inclusion criteria for such patients are:

1. Patients who have received 1.line and 2. line chemotherapy but no longer respond to
such therapy.

2. Patients who, due to toxicity of chemotherapy, cannot be offered such treatment.

3. Patients who, after meticulous information about chemotherapy, still do not want such
treatment.

4. Patients with performance status (ECOG) 0-2.

Exclusion criteria:

1. Known allergy to any of the components in Botox®

2. Known peripheral motor neuropathy disease ( for example: Amyotrophic Lateral
Sclerosis, ALS), or subclinical or clinical deficiency of neuromuscular
transmission (for example: Myasthenia Gravis or Eaton-Lambert`s Syndrome).

3. Pregnant or lactating women.

4. Another cancer disease that is not under control.

5. Another concomitant treatment for cancer.

6. Serious mental illness.

7. Performance status (ECOG) 3-4.