Inclusion Criteria:
1. Age, between 20 and 70
2. Early gastric cancer or adenoma which is achieved curative resection by endoscopic
submucosal dissection
3. ECOG performance status 0 or 1
Exclusion Criteria:
1. Previous subtotal gastrectomy or gastrostomy
2. Repeated endoscopic submucosal dissection
3. Two or more synchronous lesions
4. Presence of gastric or duodenal ulcer except artificial ulcer due to endoscopic
submucosal dissection
5. History of drugs which are able to induce gastric ulcer including aspirin, NSAIDs,
and steroid (30 days or more, within 1 year at the time of screening
6. Indication of statins, including dyslipidemia, myocardial infarction, and heart
failure.
7. Develop of complications caused by endoscopic submucosal dissection, including
bleeding, perforation, and pneumonia
8. LDL < 70 mg/dL
9. Allergy to statins
10. Pregnancy or breast milk feeding
11. Active infection
12. Significant cardiopulmonary disease
13. Active hepatitis or severe hepatic dysfunction
14. Severe renal dysfunction
15. Severe bone marrow dysfunction