Trial Information

Evaluation of the Analgesic Efficacy of the Ultrasound Guided Thoracic Paravertebral Block for Percutaneous Radiofrequency Ablation of Liver Lesions

The purpose of this study is to evaluate if single injection TPVB, ultrasound guided, ENS
assisted, is advantageous compared to deep sedation (DS)in patients undergoing percutaneous
radiofrequency ablation of liver lesions with respect to post-operative analgesia (at rest
and in movement)and vomiting. Furthermore we collect data on operator and patient
satisfaction.

In this study patients are randomly divided into two groups (20 patient each): TPVB and DS.
In TPVB group the block is performed in lateral position at level of T7 with bupivacaine
5mg/ml. In DS group the procedure is conducted under local and intravenous anesthesia, and a
post-operative analgesia is assigned. Data on patient, on procedures (duration, number and
position of lesions etc.), complications with the anesthesiological technique are collected.
The intensity of post-operative pain is assessed at 3-6-12 and 24 hours after procedure in
both group using VRS pain scale at rest and in movement. Any concomitant event like nausea,
vomiting, respiratory complications etc are recorded.